TU Delft
Education Type
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2014/2015 Applied Sciences Bachelor Nanobiology
Thermodynamics and Transport
Responsible Instructor
Name E-mail
P.E. Boukany    P.E.Boukany@tudelft.nl
Prof.dr. R.F. Mudde    R.F.Mudde@tudelft.nl
Contact Hours / Week x/x/x/x
Education Period
Start Education
Exam Period
Course Language
Course Contents
This course deals with transport of mass (or moles), momentum and energy - the
basic quantities in classical physics - at the level of cell. Most processes involve transport- or transfer in general - of these quantities.
Mass, fluid and heat transport processes are fundamental to virtually all aspect of life. For example, living systems need energy to survive. Moreover, they need new material, in the form of specific molecules to grow and reproduce or get their energy from.

-First law of thermodynamics; Equation of States; Changing States
-Entropy and second law of thermodynamics;Reversible process and work/heat;
-Entropy, Enthalpy and Gibbs Free Energy;Chemical potential

Transport phenomena:
-Microscopic theory of Diffusion; Brownian motion; Random Walks
-Macroscopic description of diffusion; Fick's equation; Diffusion through pores
-Mass transport across a thin film; Reaction-Diffusion system;
-Life at low Reynolds number; Diffusion with drift; Stokes flow; Flow through a channel; Sedimentation flow

Mathematical analysis methods: scaling and approximation techniques, analytical and numerical approaches.
Study Goals
After this course the student should:
have knowledge of the basic definitions and concepts of thermodyanmics and transport phenomena at the scale of the cell;
be able to analyse basic problems concerning heat, mass and momentum transfer in and around (living) cells;
be able to model the related processes and solve the models to obtain a quantitative description of the situation; be able to assess the outcome of the analysis using a first principle approach.
Education Method
Class room lectures followed by exercises and guided self study
Biological thermodynamics
Donald T. Haynie
Random walks in biology, Howard C. Berg
BSc: Physics 1
Note: it is absolutely required to have a good working understanding of BSc level Mathematics.
Mid term exam (Thermo) and final exam (Transport): both are of the problem solving type. During the course two take home assignments will be handed out. First assignment is related to thermodynamics and second assignment is related to transport phenomena. These assignments are graded; the grading forms part of the final mark.

Final mark = (10%) assignment-1 (Thermo) + (20%) assignment-2 (Trans) + (40%) mid-term (Thermo) + (30%) final(Trans)